Mitchell Brin has a license plate that says "Botox."
Brin's been researching Botox since 1984 and is currently the chief scientific officer of Botox at the drug company Allergan. It's one of many Botox-related license plates he owns, including some more scientific nods like one that says "Snap-25." That's a reference to a protein affected by botulinum toxin A, leading to smoother foreheads when used in the right doses.
"Botox is a big component of my life," Brin told Business Insider.
Brin is one of the scientists who saw Botox through from its early days as a potential treatment for muscle disorders to what it is today - a blockbuster pharmaceutical drug best known for cosmetic uses like smoothing out wrinkles on patients' faces.
Here's the story of how a poisonous toxin became a blockbuster treatment for everything from wrinkles to migraines.
Source: The Conversation
She wanted to know why Carruthers hadn't given her an injection near her inner brow. Carruthers explained it was because she wasn't spasming there, but the patient was insistent.
"Every time you treat me there, I get this beautiful, untroubled expression," she told Carruthers.
Carruthers took the information from that visit home with her to her husband, Alistair, who worked in dermatology. She told him she might have a solution for his patients who were struggling with their frown lines. He was sceptical, but curious to see it at work. The next day, they tested it out on their receptionist.
Over the next decade, the Carruthers went on to research and publish on the cosmetic use of Botox. Botox grew so popular that at one point in 1997, the US had run out of its supply, inciting panic for those who used the treatment monthly to reduce wrinkles.
Source: The New York Times
It took until 2002 for cosmetic Botox to officially get the FDA's stamp of approval. Since then, it's become a blockbuster drug for Allergan. In 2017 alone, the drug made $2.2 billion in revenue for both its cosmetic uses and medical uses.
Today, it's used to treat everything from crow's feet to migraines to overactive bladder. It's currently being studied in the treatment of depression.
The plan also relies on the millennial generation taking up medical aesthetics regimens, leading Allergan to launch a campaign that asks the question, "Are you bo-curious?"
Source: Business Insider
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